What is the primary function of the Endoplasmic Reticulum (ER) in a cell?

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The primary function of the Endoplasmic Reticulum (ER) is to channel materials within the cytoplasm, playing a crucial role in the synthesis, folding, modification, and transport of proteins and lipids. The ER can be classified into two types: rough ER, which is studded with ribosomes and is primarily involved in protein synthesis, and smooth ER, which is involved in the synthesis of lipids and the detoxification of certain metabolites. This organization allows the ER to effectively transport these biomolecules to specific destinations within the cell or for export outside the cell.

Understanding the ER's role in the intracellular transport system highlights its importance in maintaining cellular function, metabolism, and overall homeostasis, differentiating it from the other options that do not accurately describe its functions. For instance, while ribosomal RNA synthesis occurs in the nucleolus, the ER is not involved in that process; similarly, the storage of genetic material is a function of the cell nucleus, and waste breakdown typically happens in lysosomes, not the ER.